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  Question for our respected Pharmacist (Hoss): Post #16 (permalink)  
Old Jul. 02/09, 03:40 AM
Karky's Avatar
Karky
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well, if it upps serotonin, it would make a person less hungry.

Serotonin and the biology of feeding -- Blundell 55 (1): 155S -- American Journal of Clinical Nutrition

Quote:
Accordingly, the use of pharmacologic agents to release
5-HI and to block its reuptake produce clear reductions in hunger
and in energy intake (6 1)
Zoloft blocks reuptake.
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  Question for our respected Pharmacist (Hoss): Post #17 (permalink)  
Old Jul. 02/09, 05:26 AM
Chillen
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Quote:
Originally Posted by Karky View Post
well, if it upps serotonin, it would make a person less hungry.

Serotonin and the biology of feeding -- Blundell 55 (1): 155S -- American Journal of Clinical Nutrition



Zoloft blocks reuptake.
Exactly. Where more serotonin is available.

Quote:
Serotonin and the biology of feeding

JE Blundell

Psychology Department, University of Leeds, UK.

There is good evidence that the experimental manipulation of serotonin causes changes in feeding behavior and that adjustments in feeding and in the nutritional supply bring about responses in the level or activity of serotonin.

These data suggest that 5-HT systems in the body mediate nutritional input and the drive to feed.

In addition, it is known that serotonin is a phylogenetically primitive neurotransmitter, which may therefore occupy a central role in the relationship between food and brain organization. A framework can be developed by considering the interrelationships among feeding processes (operations of the satiety cascade), peripheral physiological mechanisms, and brain serotonin systems. Two key issues are how nutritional information is transcribed onto brain 5-HT systems and the nature of this information.

The neuroanatomical distribution of 5-HT neurons occupy an appropriate position in which to coordinate peripheral physiological and metabolic information, environmental features, and the behavioral response.
Exactly the type of material I am looking for! Thank you Karks!

I read somewhere (and I can't find it, lol), that serotonin also effects carbohydrate absorption/processing (etc, etc).


Best wishes,

Chillen

Last edited by Chillen; Jul. 02/09 at 05:29 AM.
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  Question for our respected Pharmacist (Hoss): Post #18 (permalink)  
Old Jul. 02/09, 06:18 AM
BigTomW
45h45h5hfghfghnsnfg
 
Join Date: Aug 2007
Posts: 5,157
University of Leeds info eh ^^

I'm going there September and it's where i live....

I'm so proud
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  Question for our respected Pharmacist (Hoss): Post #19 (permalink)  
Old Jul. 02/09, 06:34 AM
Karky's Avatar
Karky
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Location: had to quit when he became a mod
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Quote:
Originally Posted by Chillen View Post
Exactly. Where more serotonin is available.



Exactly the type of material I am looking for! Thank you Karks!

I read somewhere (and I can't find it, lol), that serotonin also effects carbohydrate absorption/processing (etc, etc).


Best wishes,

Chillen
I don't know how serotonin would be involved in processing of carbs, but I have heard that serotonin levels increase after a carb meal, making you feel full.
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  Question for our respected Pharmacist (Hoss): Post #20 (permalink)  
Old Jul. 02/09, 07:49 AM
Chillen
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Quote:
Originally Posted by NoLoveLost View Post
Hi Chillen

anything to help you my man


Quote:
I think part of the reason why you are finding it difficult to find any concrete info is because the research out there goes so many ways. Some (many) claim weight gain, while others weight loss. It effects so many things (as you listed) that determining how it can affect someones brain- especially when their brain is already affected by something else, makes it hard to nail down.
I read somewhere, And I have blasted some quality sites, and can't (currently) find it, where it does "things" in conjunction with other hormones, that effects certain macro-nutrient (s) (inhibits uptake, absorption, etc), and does play a part in body-weight regulation/homeostasis, and this can be different between men and women. Additionally, I am looking for some studies (specific) on why it would cause weight gain in one and loss in another-------with diet circumference included in the studies.

David is going to the doc today, as the weight loss has been too fast (actually he really needs to lose a few pounds, so this was good, if it isn't signifying an unforeseen problem). Most of the data I have read, suggests weight gain as one side effect--as most common (and sleepiness).

Additionally, I am going to call my own doctor today, and ask a few questions on his behalf. She is a hard-nosed, bottom-line, tell-it-like-is, knowledgeable, and is a nutritionist and trainer as well, and has been at family's side for many a year now.

Quote:
My son was on Zoloft for 2 years before it stopped working for him. We went thru a horrible rough patch of 6 months before we got him on Prozac and he is a happy boy again. Who knows why, but we had to switch.
Prozac, is an SSRI too isn't it? The drug thats in this, what is it called? I wonder if the side-effects (most common experienced in the masses that have been prescribed it) are near the same as the other SSRI's? Its interesting that different SSRI's that basically increase serotonin, produce different effects for some persons. Is this due to the fact that it approaches uptake in a different manner (or different place) as compared to Zoloft?


It just intrigues, me that Serotonin is so: "multi-fuinctional". I knew a small bit about it when I started researching, but I didn't really expect it to be so multidimensional within bodily functions.

Quote:
Someone already feeling depressed, may not be eating as much as they need to because they don't recognize their body's need of sustenance, and they are not aware they aren't taking in as much as they should be. (That's how I use to be. I would literally forget to eat and not even feel hungry.)

This is true. This is why, I am looking more for Abstracts/quality research, rather than "some" that have been on it (cause it doesn't really display their lifestyle habits (i.e. eating habits, other medical complications, etc, etc).

David, hasn't experienced sleepiness yet, he said today.

Quote:
I hope Mreik was able to find you some helpful information. I can only speak from what I have experienced. My best to your friend, he is lucky he has someone like you looking out for him
Yes, he did PM me, and supplied very good information, and offered more. I am going to PM him back, and see if I can get more refined information on certain topics. Mreik has been great.

I have known (David) for years and I am an extension of him, and will walk through hot coals and fire to help him. He has had my back many times as a police officer, and went with me to Iraq in 1990. He has been my friend when times were tough and when they were good, and I have his back now.

I sincerely appreciate your feed back, NLL.

Lots of love your way.


Peace.


Chillen

Last edited by Chillen; Jul. 02/09 at 08:30 AM.
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  Question for our respected Pharmacist (Hoss): Post #21 (permalink)  
Old Jul. 02/09, 08:15 AM
Karky's Avatar
Karky
Former member of VulgarityGang
 
Join Date: Dec 2005
Location: had to quit when he became a mod
Posts: 10,106
Quote:
Originally Posted by Chillen View Post




I read somewhere, And I have blasted some quality sites, and can't (currently) find it, where it does "things" in conjunction with other hormones, that effects certain macro-nutrient (s) (inhibits uptake, absorption, etc), and does play a part in body-weight regulation/homeostasis, and this can be different between men and women. Additionally, I am looking for some studies (specific) on why it would cause weight gain in one and loss in another-------with diet circumference included in the studies.

David is going to the doc today, as the weight loss has been too fast (actually he really needs to lose a few pounds, so this was good, if it isn't signifying an unforeseen problem). Most of the data I have read, suggests weight gain as one side effect--as most common (and sleepiness).

Additionally, I am going to call my own doctor today, and ask a few questions on his behalf. She is a hard-nosed, bottom-line, tell-it-like-is, knowledgeable, and is a nutritionist and trainer as well, and has been at family's side for many a year now.



Prozac, is an SSRI too isn't it? The drug thats in this, what is it called? I wonder if the side-effects (most common experienced in the masses that have been prescribed it) are near the same as the other SSRI's? Its interesting that different SSRI's that basically increase serotonin, produce different effects for some persons. Is this due to the fact that it approaches uptake in a different manner (or different place) as compared to Zoloft?


It just intrigues, me that Serotonin is so: "multi-fuinctional". I knew a small bit about it when I started researching, but I didn't really expect it to be so multidimensional within bodily functions.




This is true. This is why, I am looking more for Abstracts/quality research, rather than "some" that have been on it (cause it doesn't really display their lifestyle habits (i.e. eating habits, other medical complications, etc, etc).

David, hasn't experienced sleepiness yet, he said today.



Yes, he did PM me, and supplied very good information, and offered more. I am going to PM him back, and see if I can get more refined information on certain topics. Mreik has been great.

I have known him for years and I am an extension of him, and will walk through hot coals and fire to help him. He has had my back many times as a police officer, and went with me to Iraq in 1990. He has been my friend when times were tough and when they were good, and I have his back now.

I sincerely appreciate your feed back, NLL.

Lots of love your way.


Peace.


Chillen
Haha, Chillen is Mreik's penis
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  Question for our respected Pharmacist (Hoss): Post #22 (permalink)  
Old Jul. 02/09, 09:59 AM
NoLoveLost's Avatar
NoLoveLost
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Location: On the edge......
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Quote:
Originally Posted by Chillen View Post
I read somewhere, And I have blasted some quality sites, and can't (currently) find it, where it does "things" in conjunction with other hormones, that effects certain macro-nutrient (s) (inhibits uptake, absorption, etc), and does play a part in body-weight regulation/homeostasis, and this can be different between men and women. Additionally, I am looking for some studies (specific) on why it would cause weight gain in one and loss in another-------with diet circumference included in the studies
yeas, I have read that too. Men and women respond differently which suggest the connection between the drugs and the hormones. I've see some info about the effects on women, but have yet to see some about men.

Quote:
Originally Posted by Chillen View Post
David is going to the doc today, as the weight loss has been too fast (actually he really needs to lose a few pounds, so this was good, if it isn't signifying an unforeseen problem). Most of the data I have read, suggests weight gain as one side effect--as most common (and sleepiness).

Additionally, I am going to call my own doctor today, and ask a few questions on his behalf. She is a hard-nosed, bottom-line, tell-it-like-is, knowledgeable, and is a nutritionist and trainer as well, and has been at family's side for many a year now.
again, most of the info I have read also suggest weight gain......



Quote:
Originally Posted by Chillen View Post
Prozac, is an SSRI too isn't it? The drug thats in this, what is it called? I wonder if the side-effects (most common experienced in the masses that have been prescribed it) are near the same as the other SSRI's? Its interesting that different SSRI's that basically increase serotonin, produce different effects for some persons. Is this due to the fact that it approaches uptake in a different manner (or different place) as compared to Zoloft?
Fluoxetine:

Common side effects:

nausea, insomnia, somnolence, anorexia, anxiety, asthenia, sexual side effects, and tremors. Those that most often resulted in interruption of the treatment were anxiety, insomnia, and nervousness.

For Zoloft:

nausea, diarrhea, insomnia, loss of appetite, indigestion, dry mouth and sexual side effects

chemical make up:

Sertraline - Wikipedia, the free encyclopedia
Fluoxetine - Wikipedia, the free encyclopedia


Quote:
Originally Posted by Chillen View Post
It just intrigues, me that Serotonin is so: "multi-fuinctional". I knew a small bit about it when I started researching, but I didn't really expect it to be so multidimensional within bodily functions.
yeah, it's amazing how these drugs can effect so many aspects of our bodies...one of the reasons why I steer clear as much as possible


Quote:
Originally Posted by Chillen View Post
I have known (David) for years and I am an extension of him, and will walk through hot coals and fire to help him. He has had my back many times as a police officer, and went with me to Iraq in 1990. He has been my friend when times were tough and when they were good, and I have his back now.

I sincerely appreciate your feed back, NLL.

Lots of love your way.
You two are lucky to have each other as friends and back at ya! Your a good man, with a big heart!

Cheers!
Diane
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  Question for our respected Pharmacist (Hoss): Post #23 (permalink)  
Old Jul. 05/09, 03:05 AM
Chillen
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Join Date: May 2007
Posts: 1,856
Quote:
Originally Posted by NoLoveLost View Post

Fluoxetine:

Common side effects:

nausea, insomnia, somnolence, anorexia, anxiety, asthenia, sexual side effects, and tremors. Those that most often resulted in interruption of the treatment were anxiety, insomnia, and nervousness.

For Zoloft:

nausea, diarrhea, insomnia, loss of appetite, indigestion, dry mouth and sexual side effects

chemical make up:

Sertraline - Wikipedia, the free encyclopedia
Fluoxetine - Wikipedia, the free encyclopedia
Thank you for posting this, NLL.

Quote:
You two are lucky to have each other as friends and back at ya! Your a good man, with a big heart!

Cheers!
Diane
I never did like the doctor he goes to, and he doesn't like mine (while I just adore her), because she is pretty tough, honest, direct, calls the medical shots as she see's it, and she has the right combination of credentials. One of the things I like, is that she weeds out what is just belly-aching, whiny BS, with an actual medical problem. She says sees a lot of pure babies in her practice.

However, I convinced him to see her, this week. This is after, the doctor he sees, told him he hasn't been on it long enough, and the weight loss would subside, as it takes a few weeks........for the drug to really work well; ignoring the weight loss side effect, and not discussing other alternatives.

Uh, am I missing something here? I am going with him when he sees her this week on Tuesday.

Real/true friends are difficult to find. He is like a brother to me. We are opposites in a lot of ways.

I will post what she recommended or does on Tuesday.

Again, thank you NLL, in taking the time to post, I appreciate you.


Chillen

Last edited by Chillen; Jul. 05/09 at 03:07 AM.
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